Ibrahim F Benter Selected Research

RTKI cpd

1/2017	Src-dependent EGFR transactivation regulates lung inflammation via downstream signaling involving ERK1/2, PI3Kδ/Akt and NFκB induction in a murine asthma model.
1/2012	Activation of EGFR/ERBB2 via pathways involving ERK1/2, P38 MAPK, AKT and FOXO enhances recovery of diabetic hearts from ischemia-reperfusion injury.
10/2009	Early inhibition of EGFR signaling prevents diabetes-induced up-regulation of multiple gene pathways in the mesenteric vasculature.
8/2009	Global upregulation of gene expression associated with renal dysfunction in DOCA-salt-induced hypertensive rats occurs via signaling cascades involving epidermal growth factor receptor: a microarray analysis.

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Ibrahim F Benter Research Topics

Disease

15	Ischemia 12/2022 - 04/2004
10	Hypertension (High Blood Pressure) 08/2020 - 02/2002
6	Reperfusion Injury 01/2021 - 07/2007
6	Hyperglycemia 01/2015 - 10/2009
6	Proteinuria 05/2011 - 02/2006
5	Inflammation (Inflammations) 01/2019 - 04/2009
4	Fibrosis (Cirrhosis) 01/2019 - 07/2012
3	Metaplasia 01/2019 - 07/2012
3	Erectile Dysfunction 01/2017 - 11/2007
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2015 - 01/2013
3	Diabetes Mellitus 01/2014 - 10/2009
2	Infarction (Infarctions) 12/2022 - 01/2016
2	Cardiovascular Diseases (Cardiovascular Disease) 08/2020 - 07/2012
2	Respiratory Hypersensitivity 01/2019 - 01/2017
2	Asthma (Bronchial Asthma) 01/2019 - 07/2012
1	Cardiotoxicity 12/2022
1	Infections 08/2020
1	COVID-19 08/2020
1	Diabetic Angiopathies (Diabetic Angiopathy) 01/2019
1	Vascular Remodeling 01/2019
1	Diabetes Complications 01/2017
1	Arthritis (Polyarthritis) 07/2012
1	Spinal Cord Injuries (Spinal Cord Injury) 07/2011
1	Body Weight (Weight, Body) 03/2008
1	Left Ventricular Dysfunction 07/2007
1	Necrosis 11/2005
1	Thrombosis (Thrombus) 11/2005

Drug/Important Bio-Agent (IBA)

11	angiotensin I (1-7)IBA 12/2022 - 02/2006
7	Streptozocin (Streptozotocin)FDA Link 01/2019 - 01/2007
6	ErbB Receptors (EGF Receptor)IBA 01/2021 - 01/2012
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2016 - 11/2005
4	Dendrimers (Dendrons)IBA 12/2022 - 09/2004
4	Phosphotransferases (Kinase)IBA 01/2021 - 02/2002
4	RTKI cpdIBA 01/2017 - 08/2009
4	Proteins (Proteins, Gene)FDA Link 01/2014 - 09/2004
4	Captopril (Capoten)FDA LinkGeneric 01/2013 - 02/2006
4	ras ProteinsIBA 07/2011 - 04/2004
3	OvalbuminIBA 01/2019 - 07/2012
3	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 03/2008 - 02/2002
2	Poly(amidoamine)IBA 12/2022 - 01/2019
2	Tyrosine (L-Tyrosine)FDA Link 01/2021 - 04/2004
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 08/2020 - 01/2013
2	Angiotensin Receptor AntagonistsIBA 08/2020 - 01/2013
2	Endothelin-1 (Endothelin 1)IBA 01/2014 - 09/2012
2	20-hydroxy-5,8,11,14-eicosatetraenoic acidIBA 01/2010 - 11/2007
2	KN 93IBA 03/2008 - 02/2002
2	NG-Nitroarginine Methyl Ester (L-NAME)IBA 02/2006 - 11/2005
1	EnzymesIBA 12/2022
1	Cardiotonic Agents (Cardiac Stimulants)IBA 12/2022
1	hydroxide ionIBA 12/2022
1	PAMAM StarburstIBA 12/2022
1	src-Family KinasesIBA 01/2019
1	rho-Associated KinasesIBA 01/2019
1	SU 6656IBA 01/2017
1	CreatinineIBA 01/2016
1	Nitric Oxide Synthase (NO Synthase)IBA 01/2016
1	D-Pro7-Ang-(1-7)IBA 01/2015
1	Glucose (Dextrose)FDA LinkGeneric 01/2015
1	Lapatinib (GW572016)FDA Link 01/2015
1	Carbachol (Carbastat)FDA Link 01/2014
1	Cytochrome P-450 CYP4A (Alkane 1 Monooxygenase)IBA 01/2014
1	AngiotensinsIBA 07/2013
1	Losartan (Cozaar)FDA LinkGeneric 01/2013
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2013
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2013
1	Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA 01/2013
1	2- (4- morpholinyl)- 8- phenyl- 4H- 1- benzopyran- 4- oneIBA 01/2013
1	LigandsIBA 01/2012
1	Epidermal Growth Factor (EGF)IBA 01/2012
1	p38 Mitogen-Activated Protein KinasesIBA 01/2012
1	tyrphostin AG825IBA 01/2012
1	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2011
1	benzyloxycarbonylleucyl-leucyl-leucine aldehydeIBA 07/2011
1	UbiquitinIBA 07/2011
1	Hydralazine (Apresoline)FDA LinkGeneric 05/2011
1	Drinking WaterIBA 05/2011
1	acetovanillone (apocynin)IBA 07/2010
1	NADPH Oxidases (NAD(P)H oxidase)IBA 07/2010
1	PPAR gammaIBA 07/2010
1	CatalaseIBA 07/2010
1	Lipid PeroxidesIBA 01/2010
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2010
1	HET0016IBA 01/2010
1	TransferasesIBA 01/2010
1	AcidsIBA 01/2010
1	Hormones (Hormone)IBA 10/2009
1	SaltsIBA 08/2009
1	Desoxycorticosterone Acetate (DOCA)FDA Link 08/2009
1	NF-kappa B (NF-kB)IBA 04/2009
1	Peptides (Polypeptides)IBA 04/2009
1	Blood Glucose (Blood Sugar)IBA 03/2008
1	mitochondrial K(ATP) channelIBA 07/2007
1	Glyburide (Glibenclamide)FDA LinkGeneric 07/2007
1	Vasoconstrictor AgentsIBA 01/2007
1	ProstaglandinsIBA 02/2006
1	Indomethacin (Indometacin)FDA LinkGeneric 02/2006
1	pentaerythritolIBA 09/2004

Therapy/Procedure

2	Ligation 12/2022 - 01/2016
1	Drug Therapy (Chemotherapy) 08/2020
1	Therapeutics 07/2012